Documenti utili
In questa sezione potete trovare una serie di documenti inerenti la CBPa. Dati epidemiologici
- Primary Biliary Cirrhosis: Incidence and Predictive Factors of Cirrhosis Development in Ursodiol- Treated Patients. Christophe Choperchot, Fabrice Carrat, Raoul Poupon, Renee-Eugenie Poupon. Gastroenterology. 2002 Mar;122(3):652-8
- Evolving Trends in Female to Male Incidence and Male Mortality of Primary Biliary Cholangitis. Ana Lleo, Peter Jepsen, Emanuela Morenghi, Marco Carbone, Luca Moroni, Pier Maria Battezzati, Mauro Podda, Ian R. Mackay, M. Eric Gershwin, Pietro Invernizzi. Sci Rep. 2016 May 19;6:25906.
- The limitations and hidden gems of the epidemiology of primary biliary cirrhosis. Mauro Podda, Carlo Selmi, Ana Lleo, Luca Moroni, Pietro Invernizzi. J Autoimmun. 2013 Oct;46:81-7.
b. Stato dell’arte della CBP
- AASLD PRACTICE GUIDELINES -Primary Biliary Cirrhosis. Keith D. Lindor, M. Eric Gershwin, Raoul Poupon, Marshall Kaplan, Nora V. Bergasa, E. Jenny Heathcote
- EASL Clinical Practice Guidelines: Management of cholestatic liver diseases. Journal of Hepatology 51 (2009) 237–267
- The Global PBC Study Group. EASL, Vienna 2015. Bettina E Hansen
- A short version of a HRQoL questionnaire for Italian and Japanese patients with Primary Biliary Cirrhosis. Lorenzo Montalia, Atsushi Tanakab, Paolo Riva, Hiroki Takahashic, Claudio Cocchid, Yoshiyuki Uenoe, Massimo Miglioretti, Hajime Takikawab, Luca Vecchioa, Alessandra Frigerio, Ilaria Bianchif, Roberta Jorgensenh, Keith D. Lindorh, Mauro Poddaf, Pietro Invernizzi, the Italian-Japanese PBC Study Group. Dig Liver Dis. 2010 Oct;42(10):718-23.
- Cost and health consequences of treatment of primary biliary cirrhosis with ursodeoxycholic acid. K. M. Boberg, T. Wisløff, K. S. Kjøllesdal, H. Støvring, I. S. Kristiansen. Aliment Pharmacol Ther. 2013 Oct;38(7):794-803.
- The UK-PBC Risk Scores: Derivation and Validation of a Scoring System for Long-Term Prediction of End-Stage Liver Disease in Primary Biliary Cholangitis. Marco Carbone, Stephen J. Sharp, Steve Flack, Dimitrios Paximadas, Kelly Spiess, Carolyn Adgey, Laura Griffiths, Reyna Lim, Paul Trembling, Kate Williamson, Nick J. Wareham, Mark Aldersley, Andrew Bathgate, Andrew K. Burroughs, Michael A. Heneghan, James M. Neuberger, Douglas Thorburn, Gideon M. Hirschfield, Heather J. Cordell, Graeme J. Alexander, David E.J. Jones, Richard N. Sandford, and George F. Mells, the members of the UK-PBC Consortium. Hepatology. 2016 Mar;63(3):930-50.
- Future Economics of Liver Transplantation: A 20-Year Cost Modeling Forecast and the Prospect of Bioengineering Autologous Liver Grafts.Dany Habka, David Mann, Ronald Landes, Alejandro Soto- Gutierrez. PLoS One. 2015 Jul 15;10(7):e0131764.
- Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy. Willem J. Lammers, Gideon M. Hirschfield, Christophe Corpechot, Frederik Nevens, Keith D. Lindor, Harry L. A. Janssen, Annarosa Floreani, Cyriel Y. Ponsioen, Marlyn J. Mayo, Pietro Invernizzi, Pier M. Battezzati, Albert Parés, Andrew K. Burroughs, Andrew L. Mason, Kris V. Kowdley, Teru Kumagi, Maren H. Harms, Palak J. Trivedi, Raoul Poupon, Angela Cheung, Ana Lleo, Llorenç Caballeria, Bettina E. Hansen, Henk R. Van Buuren on behalf of the Global PBC Study Group. Gastroenterology. 2015 Dec;149(7):1804-1812.e4.
- Biochemical criteria at 1 year are not robust indicators of response to ursodeoxycholic acid in early primary biliary cirrhosis: results from a 29-year cohort study. V. Papastergiou, E. A. Tsochatzis, M. Rodriquez-Peralvarez, E. Thalassinos, G. Pieri, P. Manousou, G. Germani, C. Rigamonti, V. Arvaniti, S. Karatapanis & A. K. Burroughs. Aliment Pharmacol Ther. 2013 Dec;38(11-12):1354-64.
- The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort. Greta Pells, George F. Mells, Marco Carbone, Julia L. Newton, Andrew J. Bathgate, Andrew K. Burroughs, Michael A. Heneghan, James M. Neuberger, Darren B. Day, Samantha J. Ducker, The UK-PBC Consortium, Richard N. Sandford, Graeme J. Alexander, David E.J. Jones. J Hepatol. 2013 Jul;59(1):67-73.
- The societal burden of chronic liver diseases: results from the COME study. Luciana Scalone, Stefano Fagiuoli, Roberta Ciampichini, Ivan Gardini, Raffaele Bruno, Luisa Pasulo, Maria Grazia Lucà, Francesco Fusco, Laura Gaeta, Anna Del Prete, Giancarlo Cesana, Lorenzo Giovanni Mantovani. BMJ Open Gastroenterol. 2015 Mar 30;2(1):e000025.
- Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study. Palak J Trivedi, Willem J Lammers, Henk R van Buuren, Albert Parés, Annarosa Floreani, Harry L A Janssen, Pietro Invernizzi, Pier Maria Battezzati, Cyriel Y Ponsioen, Christophe Corpechot, Raoul Poupon, Marlyn J Mayo, Andrew K Burroughs, Frederik Nevens, Andrew L Mason, Kris V Kowdley, Ana Lleo, Llorenç Caballeria, Keith D Lindor, Bettina E Hansen, Gideon M Hirschfield on behalf of the Global PBC Study Group. Gut. 2016 Feb;65(2):321-9.
c. Informazioni cliniche e di utilizzo sull’acido obeticolico
- FDA highlights of OCALIVA prescribing information
- A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis. F. Nevens, P. Andreone, G. Mazzella, S.I. Strasser, C. Bowlus, P. Invernizzi, J.P.H. Drenth, P.J. Pockros, J. Regula, U. Beuers, M. Trauner, D.E. Jones, A. Floreani, S. Hohenester, V. Luketic, M. Shiffman, K.J. van Erpecum, V. Vargas, C. Vincent, G.M. Hirschfield, H. Shah, B. Hansen, K.D. Lindor, H.-U. Marschall, K.V. Kowdley, R. Hooshmand‑Rad, T. Marmon, S. Sheeron, R. Pencek, L. MacConell, M. Pruzanski, and D. Shapiro, for the POISE Study Group. N Engl J Med. 2016 Aug 18;375(7):631-43.
- Obeticholic Acid: First Global Approval. A. Markham, Susan J. Keam. Drugs. 2016 Aug;76(12):1221- 6
- Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid. Gideon M. Hirschfield, Andrew Mason, Velimir Luketic, Keith Lindor, Stuart C. Gordon, Marlyn Mayo, Kris V. Kowdley, Catherine Vincent, Henry C. Bodhenheimer Jr, Albert Parés, Michael Trauner, Hanns-Ulrich Marschall, Luciano Adorini, Cathi Sciacca, Tessa Beecher-Jones, Erin Castelloe, Olaf Böhm, and David Shapiro. Gastroenterology. 2015 Apr;148(4):751-61.e8.