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Portale Epatite e malattie del fegato
Malattie autoimmuni

autoimmune hepatic

Hello My brother has autoimmune hepatic for more than 14 years. The first time we knew about when he was 12 years old. He had a stomachache and itchy acne on his body. Then his skin and eyes turn yellow. Doctors found out that it is autoimmune hepatic. He had a different dosage of Ursoflor (Ursodeoxycholic Acid), Azaram (azathioprine), Prednisolone. As a result of steroid medicine (Prednisolone), he had osteoporosis last year. In addition, he got infected by a virus named CMV in his stomach. Therefore, he was hospitalized for more than 1 month in hospital last year and also had surgery on his spinal column and some therapy to cure that virus. But the pivotal issue is that now, these remedies, instead of making his liver better, don’t work for his liver and hurt other parts of his body as I mentioned. Would you mind if I ask that is there any better therapies instead of steroid which help him? Moreover, I should mention that at this time I am not in rome because I will come in fall semester as a master student of biotechnology. So, I want to know if there is new kind of therapy or new trial how it could be availible to bring my brother by myself to have this therapies? best regards Shiva Jahani
Prof.MarcoCarboneSpecialista in Gastroenterologia ed Epatologia Centro per le Malattie Autoimmuni del Fegato
Università di Milano-Bicocca ASST Grande Ospedale Metropolitano Niguarda – Milano


Questo parere non ha valenza di consulto medico e non può sostituire il colloquio, la visita e l’esame della documentazione medica del paziente.

Good morning

The standard therapy for autoimmune hepatitis is STEROIDS and AZATIOPRINE or MICOPHENOLATE MOFETIL. Unfortunately steroids can cause osteoporosis in the long run. The trick is to avoid disease recurrence and to reduce the immunosuppressive drug dosage. Other than preventing osteoporosis with vitamin D supplements and or specific drugs.
Yours sincerely

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